Top PR and Communications Firms for Regulated Healthcare Brands in the U.S.

Regulated healthcare brands in the U.S. are under the strict oversight of the FDA. However, despite popular belief, this regulation isn’t just limited to the safety, quality, and efficacy aspects of the business. The marketing and PR of regulated healthcare brands are also highly scrutinized. 

That’s why you need a reliable partner to handle the communications and public relations of your company. A specialized healthcare PR agency ensures that every press release, campaign, or claim aligns with the FDA, FTC, HIPAA, and industry-specific guidelines. 

Ready to begin? Here is a list of the top PR and communications firms for regulated healthcare brands in the U.S.

1. Avenue Z

Avenue Z specializes in addressing challenges with regulatory compliance, whether that’s with the FDA, FTC, or HIPAA. They also break down complex tech narratives into compelling storytelling to create buy-in with investors and providers. 

More importantly, they take a proprietary approach to PR and communications. At Avenue Z, that means being entirely focused on maintaining compliance, delivering data-driven results, and boosting visibility in popular outlets.

2. Edelman Health

Edelman Health has excellent media relations in the healthcare industry. Beyond earning coverage on popular outlets, they also handle crisis and issues management for FDA issues, litigation, recalls, or reputational threats under HIPAA or FDA rules. 

The agency focuses on helping regulated healthcare brands communicate clearly in complex, compliance‑driven markets. Edelman also has a medcomms arm, BioScience Communications, which creates compliant content for healthcare providers (HCPs).

3. Real Chemistry

Regulated healthcare brands facing scrutiny from the FDA may benefit from working with Real Chemistry. This PR agency specializes in preventing recalls and adverse events and staying on good terms with regulatory bodies. 

Real Chemistry uses several proprietary AI to centralize their PR strategy, such as RCIS, Swoop, and HealthGEO. They also maintain corporate reputation with the help of their new Elevate advisory practice for C-suite and investor communications.

4. Syneos Health Communications

Syneos Health Communications is the communications arm of Syneos Health, focusing entirely on healthcare PR. They specialize in creating compliant HCP content for regulated healthcare brands. That includes peer-reviewed publications, slide decks, advisory boards, and real-world evidence narratives for Phase III-IV and post-approval.

Their services also include crisis management for adverse events, FDA holds, litigation under HIPAA, or FDA compliance. This is a crucial offering for regulated healthcare brands in the U.S.

5. Finn Partners Health

Finn Partners Health handles issues and crisis management for regulatory scrutiny, adverse events, and litigation with a real-time response. However, they’re also known to secure coverage in popular healthcare outlets for product launches, trials, and policy.

Additionally, they oversee investor relations all the way from the pre-clinical stage to the commercial stage. That includes any issues with research and development delays, non-deal roadshows, and shareholder engagement.

6. Spectrum Science

Spectrum Science’s main expertise is providing compliant HCP content. They focus on key opinion leader (KOL) engagement, peer-reviewed publications, slide decks, and advisory boards that emphasize scientific accuracy and behavior change.

This agency also combines PR with omnichannel media, advertising, patient engagement, and clinical trial recruitment. They have helped many healthcare brands boost ROI using data-driven insights and optimization.

7. Russo Partners

Russo Partners specializes in handling investor relations from the pre-clinical stage to commercial. Throughout the lifecycle, they will maintain clinical updates, non-deal roadshows, and awareness campaigns to attract investors and drive funding. 

As a specialized offering, they also handle clinical trial recruitment publicity, which is a great way to boost patient enrollment. Many healthcare brands also choose them for their successful social media campaigns and sports-health alliances.

8. JPA Health

JPA Health is an independent, women-owned healthcare PR agency that secures coverage with popular healthcare outlets for launches, trials, and policy. They also handle corporate and investor comms for funding rounds and mergers and acquisitions (M&A).

JPA builds custom teams for each client and uses data and AI‑driven insights to deliver personalized support. They run commercial marketing campaigns and patient advocacy programs, supporting both awareness and adoption.

9. Health+Commerce

The main offering of Health+Commerce is translating complex science into stories for national outlets. However, they also help secure coverage for product launches, funding, and milestones to drive awareness and investor interest. 

They are also highly focused on the identity aspect of PR, which means they help healthcare brands with visuals, social media, SEO, and content creation.

10. Amendola Communications

Amendola Communications handles media relations with the help of its established healthcare journalist ties for coverage in key outlets. Their services also cover analyst relations, speaking or awards submissions, crisis comms, and media training. 

It’s a full-service program that combines PR, marketing, and internal comms for startups and enterprises alike. They also cover content development, social media programs, messaging and storytelling, and lead‑generation support. 

Find the Right PR and Communications Partner for Regulated Healthcare Brands

Healthcare brands operate under strict regulatory oversight, where messaging must balance clarity, credibility, and compliance. Working with a PR and communications firm that understands the healthcare environment can help brands navigate FDA, FTC, and HIPAA considerations while building trust with patients, providers, and stakeholders.

The firms listed above specialize in supporting regulated healthcare organizations, helping them communicate responsibly while strengthening reputation and visibility in a highly scrutinized market.

For healthcare brands looking to scale awareness while maintaining compliance, Avenue Z provides integrated communications and media strategies designed for regulated industries.